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Hyperthermia - Berlin

Patients’ information on Hyperthermia

We differ between active and passive hyperthermia.

Active hyperthermia can be equated to fever therapy. It is a very strong immuno-stimulating therapy, whereby the patient himself actively produces fever.

With a special serum Mr. Cooley, M.D., tried even in 1900 to use fever as therapeutic agent against cancer diseases. Subsequently various compounds were created, especially agents that had the power to cause fever. Unfortunately today we no longer have a ready made medical drug that contains bacteria lysates. Our active fever therapies will nowadays be induced with a special mistletoe compound (Iscador M 5 special) in combination with an alpha interferon (Intron A).

The immunologic changes that we can measure under active hyperthermia are considerable.

Opposed to this is active hyperthermia. Hereby you have an over warming therapy where the patient will receive heat from the outside. We differ between total body hyperthermia and loco-regional hyperthermia.

When applying total body hyperthermia therapy the patient’s body will be heated carefully without risking burns. When applying the so called moderate hyperthermia we reach a body cell temperature of 39° to 40°C, with extreme hyperthermia under neuroleptic analgesic (narco-similar conditions) the temperature rises to 42°C at the maximum.

Even the loco-regional deep going hyperthermia serves to intensify the effect of chemotherapeutics in those areas where the warmth is brought to. This method makes sense if metastases are localized in one ore two areas.

As a rule local hyperthermia takes place at least six times with an interval of two days in the part of the body that has to be treated.

Passive hyperthermia is no cancer therapy of its own; it rather serves to intensify the effect of chemotherapeutics and only makes sense in combination of chemotherapeutics or radio-therapy. Various cytotoxics will strongly be increased in their efficiency by warmth without intensifying the side effects.